On this day, April 19, 1943  Albert Hoffmann, a 37 year old chemist for 
Sandoz, in Basel, Switzerland, ingested intentionally a  minute 
amount—just 250 
micrograms--of a compound derived from the ergot fungus thus 
synthesizing  lysergic acid diethylamide for the first time.Three days 
earlier, he had 
absorbed a small amount of the drug either through his fingertips or by 
accidentally ingesting it. Anyway, less than an hour later, Hoffman
began to feel strange and noticed 
sudden and intense changes in his perception. He decided to pedal home 
from his laboratory. His bike ride accompanied by strong hallucinations 
developed into a real trip. Hoffman turned on, tuned in, becoming the 
first human to trip on LSD. This is how Hoffman learned about 
the effects of this substance and  experienced all its
 heavenly and hellish effects.
 Hofmann realized he had made a significant discovery: a psychoactive
 substance with extraordinary potency, capable of causing significant 
shifts of consciousness in incredibly low doses. He 
wrote about his 
experiments and experience on April 22, which was later put into his 
book LSD: My Problem Child.
He saw the drug as a powerful 
psychiatric tool,  because of its intense and 
introspective nature, he couldn’t imagine anyone using it 
recreationally.
Hoffman admitted that the substance would be 
dangerous in the wrong hands. Look at the sad tale of Syd Barrett and 
others, we've all probably encountered, the same drug that awakens us 
can also enslave us or drive us mad. 
Albert Hofmann  had first synthesized lysergic 
acid diethylamide (LSD) on November  16, 1938, while researching lysergic 
acid derivatives. The main intention of the synthesis was to obtain an 
analeptic (a central nervous system stimulant).
Researchers
 were looking initially  at ways of identifying and synthesizing 
chemical compounds from plants. Hofmann
 chose ergot, a fungus that grows on rye and other cereals, which was 
formerly used by midwives to stop bleeding after childbirth. It also 
causes ergotism, a form of fungal poisoning, which was a common 
complaint among medieval pilgrims.
Hofmann managed to isolate some of
 ergot's active substances, including a drug that stops post-natal 
haemorrhaging.But he is best remembered for his accidental discovery of 
LSD .. 
After Hoffman’s discovery, psychologists 
clinically researched the drug throughout the 40s, 50s, and 60s, with 
the Swiss company Sandoz Pharmaceuticals distributing free samples of 
the chemical for research purposes.Alfred Hubbard read
 a report discussing the hallucinogenic effects of the then-obscure drug
 and tried it in 1951. He became known as the first true proponent for 
LSD outside of the research world after realizing that it could be used 
to explore the depths of the human psyche. He began researching and 
distributing the compound, eventually swapping his LSD for psilocybin, 
the psychoactive chemical in certain mushrooms, being studied by a 
Harvard psychologist, Dr.Timothy Leary.
Leary went on to become the most 
high-profile researcher and proponent of the drug, eventually losing his
 position at Harvard for the controversial nature of his advocacy. He 
published The Psychedelic Experience: A Manual Based on the Tibetan Book of the Dead with Richard Alpert in
 1964, a work that compared the nature of tripping to the spiritual 
experience of birth and rebirth detailed in the Tibetan tome.Leary identified  phases of
 the psychedelic experience with the  Bardo stages of consciousness 
outlined in the Tibetan Book of the Dead,from "complete transcendence" 
to " routine game reality " and indeed the arrival of LSD coincided with a
 surge of interest in mystical  and esoteric subjects He 
advocated for students to “Turn on, tune in, and drop out,” a message 
that was picked up by the counterculture and perpetuated with the rising
 prevalence of acid parties.
Ken Kesey served as a 
medical guinea pig testing LSD and other psychoactive drugs in the 
1950’s (at the time, the CIA was also testing LSD as a weapon as part of
 its MKUltra program, thinking that it could be used as “truth sermon” 
or to incapacitate enemy forces). After publishing One Flew Over The Cuckoo’s Nest
 in 1962, a book detailing his experiences during the research project, 
the financial success of the book allowed him to move to California, 
where he began hosting a series of “Acid Tests” in San Francisco along 
with his gang of Merry Pranksters. Enter the Grateful Dead, then known as The Warlocks 
 who served as the house band for these tests, during which attendees 
dropped acid and explored LSD’s mind-altering effects.
The 1960's,  saw LSD use became widespread among people who sought to 
alter and intensify  their perceptual experience, to achieve insights 
into the universe and themselves, and to deepen emotional connection 
with others.
At the helm of the counterculture revolution of the 60s and beyond, 
increasingly, the government became worried about the use of the drug, 
associating it with the anti-war sentiment and viewing it as a threat to
 American middle class, traditional values. After Dr. Sidney Cohen, a 
doctor who tested the psychoanalytical capabilities of the compound, 
testified before Congress in 1966 and declared that the drug was 
dangerous in the wrong hands, LSD was made illegal in 1967.
 Hofmann called LSD "medicine for the soul" and was frustrated by the 
worldwide prohibition that has pushed it underground. "It was used very 
successfully for 10 years in psychoanalysis," he said, adding that the 
drug was hijacked by the youth movement of the 1960's and then unfairly 
demonized by the establishment that the movement opposed. 
While the counterculture raged on, with time the popularity of LSD 
subsided in the 80s, as other drugs became en vogue. However, as the 
turn of the new millennium approached, so did the youth’s interest in 
the psychedelic compound, with the drug reemerging in popularity in the 
90’s and into the 2000’s through to now.
 Psychedelic enthusiasts  across the world now commemorate Hoffman's 
discovery of LSD's effects every April 19, a.k.a. "Bicycle Day. "  The first celebration took place in 1985. It was initiated by Thomas B. Roberts of DeKalb, Illinois. 
Albert Hoffman's amazing discovery  has subsequently contributed to 
countless works of art, literature, and music. Releasing a rich banquet 
of inspiration that still manages to fuel our senses today. From the 
books of Aldous Huxley, Kurt Vonnegut , Jr, to the music of Jimi 
Hendrix, my local heros Sendelica, acid still catches the imagination.
 I've personally taken a few trips in my time, not for a while though, 
never seem to come across  it,  perhaps people are hiding it from me, 
because they've seen me under the influence, managed to hitch to 
glastonbury from west wales, under the influence , stopping on way back for some respite in a
 field by the motorway for a while, to gather my senses and spend time 
talking to a tree. Happy days. Oh and I have a flying frog in my living 
room called Albert. 
 
 My frog who goes by the name of Albert